• Nana Asiedu, Irene Kretchy, and Emmanuel Asampong.
• University of Ghana College of Health Sciences, Social and Behavioural Sciences, School of Public Health.
• Afr Health Sci. 2020 Jun 1; 20 (2): 487-596.

BackgroundIt is estimated that almost half of all people living with HIV have some form of neurocognitive impairment, but few studies have looked at the risk of neurocognitive impairment and its associated factors in Ghana, due in part to limited resources for such testing.ObjectivesTo examine neurocognitive performance in a group of Ghanaians living with HIV and possible factors that contribute to their performance.MethodsOne hundred and four patients were assessed using a selection of brief non-invasive neuropsychological assessments as well as the International HIV Dementia Scale. Psycho-behavioural factors (alcohol use, depression, and medication adherence) as well as demographic characteristics and functional daily activities were assessed to determine their association with neurocognitive performance, using linear regression and receiver operating characteristic analyses.ResultAbout 48% of the participants met the criteria for risk of neurocognitive impairment. Age, education, and symptoms of depression were found to be significantly associated with the risk of impairment.ConclusionSome people living with HIV showed risk of neurocognitive impairment, which was significantly associated with education, age and depressive symptoms. It is therefore important to consider routine neurocognitive screening in HIV management to recognize any risks for early interventions.© 2020 Asiedu N et al.

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