• Jingjie Feng, Congcong Zhou, Cheng He, Yuan Li, and Xuesong Ye.
• Biosensor National Special Laboratory, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, People's Republic of China.
• Physiol Meas. 2017 Apr 1; 38 (4): 652-668.

ObjectiveIn this paper, a miniaturized wearable core body temperature (CBT) monitoring system based on the dual heat flux (DHF) principle was developed.ApproachBy interspersing calcium carbonate powder in PolyDimethylsiloxane (PDMS), a reformative heat transfer medium was produced to reduce the thermal equilibrium time. Besides, a least mean square (LMS) algorithm based active noise cancellation (ANC) method was adopted to diminish the impact of ambient temperature fluctuations. Theoretical analyses, finite element simulation, experiments on a hot plate and human volunteers were performed.Main ResultsThe results showed that the proposed system had the advantages of small size, reduced initial time (~23.5 min), and good immunity to fluctuations of the air temperature. For the range of 37-41 °C on the hot plate, the error compared with a Fluke high accuracy thermometer was 0.08  ±  0.20 °C. In the human experiments, the measured temperature in the rest trial (34 subjects) had a difference of 0.13  ±  0.22 °C compared with sublingual temperature, while a significant increase of 1.36  ±  0.44 °C from rest to jogging was found in the exercise trial (30 subjects).SignificanceThis system has the potential for reliable continuous CBT measurement in rest and can reflect CBT variations during exercise.

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