• Cleve Clin J Med · Feb 2020

    Review

    Pharmacogenomics: An evolving clinical tool for precision medicine.

    • Jennifer K Hockings, Amy L Pasternak, Angelika L Erwin, Neil T Mason, Charis Eng, and J Kevin Hicks.
    • Department of Pharmacy, Cleveland Clinic; Genomic Medicine Institute, Lerner Research Institute, and Center for Personalized Genetic Healthcare, Cleveland Clinic Community Care hockinc@ccf.org.
    • Cleve Clin J Med. 2020 Feb 1; 87 (2): 91-99.

    AbstractPharmacogenomics, ie, the study of how an individual's genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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