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Review Historical Article
The Evolution of Corpus Callosotomy for Epilepsy Management.
- Aparna Vaddiparti, Richard Huang, David Blihar, Maira Du Plessis, Michael J Montalbano, R Shane Tubbs, and Marios Loukas.
- Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.
- World Neurosurg. 2021 Jan 1; 145: 455-461.
AbstractCorpus callosotomy, first used in the management of epilepsy by William P. van Wagenen in 1940, was for years a contentious procedure. Two decades later, Nobel Laureate Roger W. Sperry's split-brain studies inspired surgeons to reexamine the role of corpus callosotomy in the control of epileptic seizures. In 1962, Joseph Bogen and Philip Vogel performed complete corpus callosotomies in patients with a history of generalized seizures. The identification of a set of postsurgical disconnection symptoms and other neurologic deficits begged the improvement of the surgical technique. Modifications to the operation, including anterior callosotomy, posterior callosotomy, partial callosotomy, staged callosotomy, microsurgical techniques, and radiosurgical techniques, continue to refine the procedure.Copyright © 2020 Elsevier Inc. All rights reserved.
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