• Yasmin Raashid, Ayesha Ali, Yasmin Ehsan, Hussain Jafri, Imran Waheed, Gerald Mason, and Naeem Majeed.
• Private Practice, Lahore, Pakistan.
• J Coll Physicians Surg Pak. 2020 Nov 1; 30 (11): 1193-1196.

ObjectiveTo determine the perinatal outcome of pregnancies complicated by Rh-alloimmunisation, requiring intrauterine blood transfusion.Study DesignObservational study.Place And Duration Of StudyFeto-maternal Unit of Gene Tech Laboratory, Lahore, from 2007 to 2019.MethodologyA retrospective analysis was done on the data of cases of intrauterine, intravascular blood transfusion given to at-risk foetuses to correct foetal anaemia due to Rh-alloimmunisation or parvovirus B19. All cases, who were eligible to receive IUBT were included in the study. Cases where historic data was not available have been excluded.ResultsA total of 305 intrauterine blood transfusion (IUBT) procedures were performed on 127 foetuses. The gestational age ranged from 18-32 weeks at the time of referral. Infra-hepatic part of umbilical vein was preferred for transfusion, but in some cases of anterior placenta, the cord insertion was approached with exception of only two cases where intra-cardiac route was employed. In this study, 71.6% of the babies survived, 14.2% were loss to follow and 14.2% died.ConclusionIUBT is a safe procedure, especially when performed by experienced hands, and helps save the foetuses at risk. Mothers with Rh-alloimmunisation should be referred before developing hydrops fetalis for better outcome. Key Words: Red cell alloimmunisation, Intrauterine intravascular blood transfusion, Foetal anaemia.

15 keywords...

hide…