• Cleve Clin J Med · Jun 2021

    Update to coagulopathy in COVID-19: Manifestations and management.

    • Simon R Mucha, Siddharth Dugar, Keith McCrae, Douglas Joseph, John Bartholomew, Gretchen L Sacha, and Michael Militello.
    • Critical Care Medicine, Respiratory Institute, Cleveland Clinic; Clinical Instructor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
    • Cleve Clin J Med. 2021 Jun 2.

    AbstractSevere COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19-associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients with COVID-19, with more aggressive prophylaxis and screening recommended for critically ill patients with D-dimer levels above 3.0 μg/mL. Point-of-care ultrasonography is the imaging method of choice for patients at high risk, as it entails minimal risk of exposing providers to the virus.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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