• Chinese medical journal · Dec 2020

    Review

    An update on the role of long non-coding RNAs in psoriasis.

    • Jian-Kun Song, Shuang-Yi Yin, Wei Li, Xiao-Dong Li, Yue Luo, Ying Luo, Meng Xing, Bin Li, and Le Kuai.
    • Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
    • Chin. Med. J. 2020 Dec 11; 134 (4): 379-389.

    AbstractIncreasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells.Copyright © 2021 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

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