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- L V Lysenko Kozlovskaya, V V Rameev, and T V Androsova.
- Sechenov First Moscow State Medical University (Sechenov University).
- Terapevt Arkh. 2020 Jul 9; 92 (6): 15-22.
AbstractIn this article we discussed the current state of monoclonal gammapathy of renal significance (Monoclonal Gammopathy of Renal Significance MGRS) and revealed problems of B-cell clone secreting nephrotoxic monoclonal immunoglobulin identification. We followed 276 patients with monoclonal gammapathy including patients with non-amyloid nephropathy. The majority of patients had systemic AL-amyloidosis. We established better survival of the treated patients with systemic AL-amyloidosis in comparison with retrospective untreated cohort. We considered current treatment of patients with non-amyloid nephropathy and focused on the crucial role of multidisciplinary approach in management of these patients.
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