• Anesthesia and analgesia · Mar 1977

    Comparative Study Clinical Trial

    A comparison of glycopyrrolate and atropine during reversal of nondepolarizing neuromuscular block with neostigmine.

    • G W Ostheimer.
    • Anesth. Analg. 1977 Mar 1; 56 (2): 182-6.

    AbstractGlycopyrrolate and atropine were compared as to their effects on heart rate, arrhythmias, blood pressure, and volume of oropharyngeal secretions. Glycopyrrolate protects against neostigmine-induced bradycardia, produces less initial tachycardia, causes a lower incidence of cardiac arrhythmias, and is a superior oropharyngeal drying agent. Use of this drug instead of atropine should be considered during reversal of nondepolarizing neuromuscular block.

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