Anesthesia and analgesia
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Anesthesia and analgesia · Mar 1977
Comparative StudyArrhythmic doses of epinephrine and dopamine during halothane, enflurane, methoxyflurane, and fluroxene anesthesia in goats.
The cardiac arrhythmicity of epinephrine and dopamine was compared in awake goats and during approximate equivalent levels of halothane, enflurane, methoxyflurane, and fluroxene anesthesia. The arrhythmic threshold dose for epinephrine and dopamine was significantly (p less than 0.05) reduced during halothane anesthesia when compared to values determined in awake animals. ⋯ Epinephrine produced greater elevations in mean arterial pressure than dopamine with all anesthetics except enflurane, and dopamine produced significantly (p less than 0.05) higher heart rates in the awake animals and those anesthetized with halothane and enflurane. The authors conclude that, in terms of arrhythmic potential, there is no advantage in the use of dopamine rather than epinephrine for the reversal of halothane-induced myocardial depression during halothane or enflurane anesthesia.
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Anesthesia and analgesia · Mar 1977
Comparative StudyA comparison of general anesthesia and lumbar epidural analgesia for elective cesarean section.
Controversy exists concerning the choice of anesthetic technic for elective cesarean section. Several maternal and newborn parameters were compared during general anesthesia (GA) and lumbar epidural analgesia (LEA). ⋯ Umbilical artery and vein pH were better with GA, but 1-minute Apgar-minus-color scores were higher and time to sustained respiration was shorter with LEA. On the basis of this study, neither technic can be vigorously recommended over the other from the standpoint of the newborn's condition.
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Anesthesia and analgesia · Mar 1977
Comparative Study Clinical TrialA comparison of glycopyrrolate and atropine during reversal of nondepolarizing neuromuscular block with neostigmine.
Glycopyrrolate and atropine were compared as to their effects on heart rate, arrhythmias, blood pressure, and volume of oropharyngeal secretions. Glycopyrrolate protects against neostigmine-induced bradycardia, produces less initial tachycardia, causes a lower incidence of cardiac arrhythmias, and is a superior oropharyngeal drying agent. Use of this drug instead of atropine should be considered during reversal of nondepolarizing neuromuscular block.
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Anesthesia and analgesia · Mar 1977
Fade of neurally evoked compound electromyogram during neuromuscular block by d-tubocurarine.
Trains of neurally evoked compound electromyographic responses of the thenar muscles were studied in 20 patients anesthetized with enflurane and N2O and paralyzed with d-tubocurarine. Fade was correlated with stimulus frequency (0.1 to 50 Hz) and degree of neuromuscular block. ⋯ Fade was more observable with deeper block and could best be demonstrated by 5 Hz stimuli. With 50 Hz stimuli, a concomitant facilitation, observable from the beginning of the train, partially compensated for the fade.