• Sabrina Touati, Rachid Djekkoun, Mohamed El-Hadef El-Okki, and Dalila Satta.
• Laboratory of molecular and cellular biology, Mentouri Brothers University, Constantine, Algeria.
• Afr Health Sci. 2020 Sep 1; 20 (3): 125012581250-1258.

BackgroundGliomas are a relatively rare group of tumors with a poor prognosis. We aimed to describe and analyze the clinical characteristics and survival of patients with glioma tumors of Eastern Algeria.MethodsA retrospective study was conducted at the University Hospital of Constantine. Medical records of patients enrolled between January 2008 and October 2016 were consulted. Demographic characteristics, clinical data, treatment strategy and dates of last follow-up or death were collected. Chi-square test was used for checking associations, Kaplan-Meier methodology for estimating the survival, and the cox model for identifying prognosis factors.ResultsA total of 333 patients composed our cohort. The mean age was 48.07 years, and men were 1.87 times more frequent than women. High grade tumors were mainly observed among adults and old adults and in supra-tentorial locations. More than half of the patients had a large resection and a curative protocol of oncological treatment (50.7% and 57%, respectively). The mean overall survival was 45.4 months, the median was 21.7 months, and survival rates at 1-, 2-, and 5-years were: 62.8%, 48.5% and 32.9% respectively. Age, histology, grade of malignancy and oncological treatment were the major prognosis factors.ConclusionOur sample was relatively young with a higher survival compared to others.© 2020 Touati S et al.

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