• Gynecol. Endocrinol. · Dec 2006

    Review

    Clinical applications of mifepristone.

    • Oi Shan Tang and Pak Chung Ho.
    • Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong, SAR, China. ostang@graduate.hku.hk
    • Gynecol. Endocrinol. 2006 Dec 1; 22 (12): 655-9.

    AbstractMifepristone is a progesterone antagonist that has been studied for a number of clinical applications. It is a well-known abortifacient that is effective for both first- and second-trimester medical abortion when used with a prostaglandin analog. It is also an effective cervical priming agent that can be used to soften the cervix before surgical evacuation. Its clinical efficacy as an emergency contraception has been proven. Other applications including treatment for fibroids, endometriosis and various cancers have been explored. However, its association with abortion limits the applications of mifepristone in many of these areas.

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