• Abdulaziz M Alyami, Naoufel M Kaabia, Marzouq A AlQasim, Fahad S Al Doghaim, Lulu B Albehlal, Medina A Ahmed, Amal Y Al Aidaroos, and Abdurahman Al Odayani.
• Infection Control and Prevention Department, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail. amyami@psmmc.med.sa.
• Saudi Med J. 2020 Mar 1; 41 (3): 309-313.

ObjectivesTo describe the epidemiological, clinical, and outcome data of patients infected or colonized with Chryseobacterium/Elizabethkingia spp including antibiotic susceptibility patterns.MethodsThis retrospective study was conducted at Prince Sultan Military Medical City, Riyadh,  Saudi Arabia. All patients infected or colonized by Chryseobacterium /Elizabethkingia spp who were admitted between June 2013 and May 2019 were included. Data were extracted from patient electronic medical records.ResultsWe enrolled 27 patients (13 males and 14 females) with a mean age of 35.6 years. Chryseobacterium/Elizabethkingia spp were isolated from blood cultures (n=13, 48%) and tracheal aspirations (n=11, 41%). The most frequent species isolated was Elizabethkingia meningoseptica (n=22). Although 6 patients were considered colonized, the remaining 21 patients presented with ventilator associated pneumonia (n=9), central line associated bloodstream infection (n=4), septic shock (n=4), or isolated bacteremia (n=4). In 25 cases the infections were health-care related. Three patients (11%) died within 28 days. Twenty-six isolates (96.5%) were resistant to carbapenems. Moxifloxacin and cotrimoxazole were the most active antibiotics.ConclusionChryseobacterium/Elizabethkingia spp infection is rare, but can be responsible for severe hospital acquired infections. Cotrimoxazole and fluoroquinolone are the most effective antibiotic treatments.

34 keywords...

hide…