• Ibrahim Omerhodžić, Mirza Pojskić, Krešimir Rotim, Bruno Splavski, Lukas Rasulić, and Kenan I Arnautovic.
• 1Department of Neurosurgery, Sarajevo University Clinical Center, Sarajevo, Bosnia and Herzegovina; 2Department of Neurosurgery, University of Marburg, Marburg, Germany; 3Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia; 4University of Applied Health Sciences, Zagreb, Croatia; 5Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 6Josip Juraj Strossmayer University of Osijek, School of Dental Medicine and Health, Osijek, Croatia; 7Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia; 8Semmes Murphey Neurologic & Spine Institute, Memphis, TN, United States; 9Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, United States.
• Acta Clin Croat. 2020 Jun 1; 59 (2): 329-337.

AbstractMyxopapillary ependymomas (MPE) of the spinal cord are slow-growing benign tumors most frequently found in adults between 30 and 50 years of age. They arise from the ependyma of the filum terminale and are located in the area of the medullary conus and cauda. The recommended treatment option is gross total resection, while patients undergoing subtotal resection usually require radiotherapy. Complete resection without capsular violation can be curative and is often accomplished by simple resection of the filum above and below the tumor mass. Nevertheless, dissemination and distant treatment failure may occur in approximately 30% of the cases. In this paper, we propose an original MPE classification, which is based upon our personal series report concerned with tumor location and its correlation with the extent of resection. We also provide literature review, discussing surgical technique, tumor recurrence rate and dissemination, and adjuvant treatment. In conclusion, our findings suggest that MPE management based on the proposed 5-type tumor classification is favorable when total surgical resection is performed in carefully selected patients. Yet, further studies on a much broader model is obligatory to confirm this.

15 keywords...

hide…