• James E Manning, Todd E Rasmussen, Samuel A Tisherman, and Jeremy W Cannon.
• From the Department of Emergency Medicine (J.E.M.), School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Surgery (T.E.R., J.W.C.), F. Edward Hébert School of Medicine at the Uniformed Services University; R. A. Cowley Shock Trauma Center (S.A.T.), University of Maryland School of Medicine, Baltimore, Maryland; Division of Traumatology, Surgical Critical Care & Emergency Surgery, Department of Surgery (J.W.C.), Perelman School of Medicine at the University of Pennsylvania; and Leonard Davis Institute of Health Economics (J.W.C.), University of Pennsylvania, Philadelphia, Pennsylvania.
• J Trauma Acute Care Surg. 2020 Aug 1; 89 (2S Suppl 2): S50-S58.

AbstractThis article reviews four emerging endovascular hemorrhage control and extracorporeal perfusion techniques for management of trauma patients with profound hemorrhagic shock including hemorrhage-induced traumatic cardiac arrest: resuscitative endovascular balloon occlusion of the aorta, selective aortic arch perfusion, extracorporeal life support, and emergency preservation and resuscitation. The preclinical and clinical studies underpinning each of these techniques are summarized. We also present an integrated conceptual framework for how these emerging technologies may be used in the future care of trauma patients in both resource-rich and austere environments.

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