• J Coll Physicians Surg Pak · Mar 2020

    Observational Study

    Prediction of Lymph Node Metastasis in Colon Cancer via Platelet to Lymphocyte Ratio and Platelet Count.

    • Oguz Catal, Bahri Ozer, and Mustafa Sit.
    • Department of General Surgery, Abant Izzet Baysal University Hospital, Bolu, Turkey.
    • J Coll Physicians Surg Pak. 2020 Mar 1; 30 (3): 250-253.

    ObjectiveTo investigate the value of preoperative blood tests in predicting lymph node metastasis in colon cancer patients undergoing surgery.Study DesignObervational study.Place And Duration Of StudyGeneral Surgery Department, Bolu Abant Izzet Baysal University Medicine School, Turkey, between December 2012 and December 2018.MethodologyIn 171 colon cancer patients, preoperative inflammatory markers such as albumin, C-reactive protein (CRP), platelet, neutrophil-to-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) counts were determined.ResultsThe present study albumin, CRP and NLR values were also not significantly different between the groups. PLR (p=0.008) and PLT (p=0.039) were significantly different between the lymph node groups. ROC analysis was performed for PLT and PLR for the prediction of lymph node metastasis (Group 2 and 3). Accuracy for PLT was 0.623 and accuracy for PLR was 0.65. A PLT value >321.5 was found to be 63.7% sensitive and 68.6% specific in predicting lymph node metastasis. A PLR value >155.81 was 70% sensitive and 41% specific for predicting lymph node metastasis.ConclusionThe platelet counts and PLR values are important in predicting lymph node metastasis in colon cancer, preoperatively. Platelet and PLR values may be more specific and sensitive in predicting preoperative lymph node metastasis in colon cancer patients.

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