• J Coll Physicians Surg Pak · Mar 2020

    Case Reports

    Neuromyelitis Optica as an Initial Presentation of Systemic Lupus Erythematosus in a Young Male.

    • Sadaf Iftikhar, Adnan Mahmood, and Masooma Hashmat.
    • Department of Neurology, King Edward Medical University / Mayo Hospital, Lahore, Pakistan.
    • J Coll Physicians Surg Pak. 2020 Mar 1; 30 (3): 321-323.

    AbstractAquaporin-4 antibodies are hallmark of neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorders (NMOSD) that are distinct disease entities. We report a 24-year male with NMO, who presented with Brown-Sequard syndrome. Clinical and laboratory parameters confirmed the diagnosis of systemic lupus erythematosus (SLE). Involvement of sympathetic trunk causing Horner's syndrome and a wide time lapse of 13 years from the occurrence of optic neuritis to myelitis with no relapses in between is a rarity to be seen in NMO associated with SLE.

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