• Yulin Liu, Fei Chen, Weibing Zhao, and Ying Zhu.
• Department of Anesthesiology, Chongqing Emergency Medical Center (Chongqing University Central Hospital), Chongqing, China.
• J Coll Physicians Surg Pak. 2021 Jan 1; 31 (1): 8-13.

ObjectiveTo determine the correlation of old age, pulmonary artery pressure (PAP) and mean arterial blood pressure (MABP) during anesthetic induction in elderly patients.Study DesignProspective cohort study.Place And Duration Of StudyCentral Hospital affiliated to Chongqing Medical University from September 2016 to September 2019.MethodologyA total of 75 elderly patients with pulmonary hypertension, who underwent surgery under general anesthesia, were inducted. Each 25 patients were allocated into 65-74 years, 75-84 years, and ≥85 years groups. PAP was invasively measured using a right heart floating catheter before induction, while MAP was measured using an invasive radial artery catheter at one minute before and within five minutes after anesthetic induction.ResultsPAP and PAMP, both increased with age (p <0.001). MAP at one minute before induction significantly increased with aging, while MAP measured at 1, 3 and 5 minutes after anesthetic induction, exhibited tendencies of significant decrease with aging (p <0.05). The correlation analysis results revealed that mean MAP during anesthesia induction was significantly associated with PASP before induction (r = -0.384 and -0.532 for Kendall and Spearman correlation analyses; both p<0.05).ConclusionIncreased PAP may be involved in the association between with aging and increased risk of hypotension during induction. Key Words: General anesthesia, Hypotension, Pulmonary arterial blood pressure, Old age.

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