• World Neurosurg · May 2021

    Early Experience Of Endoscopic Endonasal Transphenoidal Surgery For Pituitary Adenoma. Preliminary Report Of 56 Cases Operated In A West African Institution.

    • Meleine Landry Konan, Aderehime Haidara, Wilfried M Meuga, Grace Djondé, Sidoine M Gbazi, Marcel Okamon, Louis K Derou, and Dominique Ndri Oka.
    • Department of Neurosurgery, Teaching Hospital of Yopougon, University Felix Houphouet Boigny, Abidjan, Cote d'Ivoire. Electronic address: landrix07@gmail.com.
    • World Neurosurg. 2021 May 1; 149: e329-e335.

    BackgroundAlthough endoscopic endonasal approach (EEA) has been popularized worldwide for pituitary adenoma surgery, in sub-Saharan Africa, neurosurgeons are still only starting their experience with it. This study was designed to assess the early results of EEA for pituitary adenoma from an under-equipped environment, namely, the Department of Neurosurgery of the Teaching Hospital of Yopougon Abidjan and Bouaké in Ivory Coast.MethodsThe data of 56 cases of EEA for pituitary adenoma surgery performed between 2016 and March 2019 at the Teaching Hospital of Yopougon-Abidjan and Bouaké were retrospectively assessed. Pre- and postoperative neuro-ophthalmologic and hormonal status were analyzed. Moreover, the quality of tumor removal, and pre- and postoperative complications were also evaluated.ResultsIn this study, there were nonfunctional adenomas (20), prolactinoma (18), Cushing disease (9), and acromegaly (3). A reduced visual acuity and/or visual field defect was observed in 49 cases. The mean operation time was 225 ± 94.7 minutes. The tumor removals were complete in 57.14%, subtotal in 35.71%, and partial in 7.14%. These led to a visual improvement in 69.64%. Postoperative complications were cerebrospinal fluid leaks (19.64%), diabetes insipidus (12.50%), visual worsening (7.14%), meningitis (3.57%), and carotid injury (3.57%) that led to death.ConclusionsThis study represents the early surgical experience using EEA for treating pituitary adenoma in an under-equipped environment. Although the postoperative complication rate was relatively high, refinements of local surgeons' technique would lead to a better patient outcome.Copyright © 2021 Elsevier Inc. All rights reserved.

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