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- J Coulson, L Bagley, Y Barnouin, S Bradburn, G Butler-Browne, H Gapeyeva, J-Y Hogrel, T Maden-Wilkinson, A B Maier, C Meskers, C Murgatroyd, M Narici, M Pääsuke, L Sassano, S Sipilä, N Al-Shanti, L Stenroth, D A Jones, and J S McPhee.
- School of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, M15GD, UK.
- Osteoporos Int. 2017 Sep 1; 28 (9): 2683-2689.
AbstractBone mineral density declines with increasing older age. We examined the levels of circulating factors known to regulate bone metabolism in healthy young and older adults. The circulating levels of dickkopf-1, osteocalcin, osteoprotegerin and sclerostin were positively associated with whole-body bone mineral density (WBMD) in older adults, despite the average WBMD being lower and circulating dickkopf-1, osteoprotegerin and sclerostin being higher in old than young.
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