• Mingyu Ren, Yixiang Wu, Ruimiao Li, Jingjing Wang, Limin Liu, and Yu Gao.
• Department of Orbital Disease and Ocular Tumor, Hebei Eye Hospital, Xingtai, Hebei Province, China.
• Medicine (Baltimore). 2021 Feb 19; 100 (7): e24801.

RationaleOrbital schwannoma is a relatively rare orbital tumor, and calcification of the lesion is rarely found in the orbit. We report a case of orbital schwannoma which was characterized by calcification in the orbital muscle cone, and was cured by intracapsular excision.Patient ConcernsA 54-year-old female with a complaint of a mass in the left orbit during a magnetic resonance imaging examination and symptom of dizziness 6 months before, presented with painless exophthalmos and vision decline in the left eye.DiagnosesAccording to clinical manifestations, imaging examinations and postoperative immunohistochemical examinations, the diagnosis was orbital schwannoma, with calcification in the muscle cone.InterventionsThe patient was treated by intracapsular excision of the left orbit. We removed the intracapsular mass and most part of the cyst wall in order to prevent orbital apex syndrome.OutcomesThe diagnosis of schwannoma with calcification was confirmed finally through histological and immunohistochemical exam. The patient was followed up for 28 months and the orbital CT scan showed that there were no significant lesions found in the orbital muscle cone.LessonsUnderstanding clinical, imaging diagnostic, and histopathological features of rare orbital schwannoma with calcification will facilitate timely diagnosis and treatment of this condition. The intracapsular excision can help in avoiding complications.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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