• Richard Rezar, Bernhard Wernly, Michael Haslinger, Clemens Seelmaier, Philipp Schwaiger, Ingrid Pretsch, Maria Eisl, Christian Jung, Uta C Hoppe, and Michael Lichtenauer.
• Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, 5020, Salzburg, Austria. r.rezar@salk.at.
• Wien. Klin. Wochenschr. 2021 May 1; 133 (9-10): 492-499.

BackgroundPerforming cardiopulmonary resuscitation (CPR) and postresuscitation care in the intensive care unit (ICU) are standardized procedures; however, there is evidence suggesting sex-dependent differences in clinical management and outcome variables after cardiac arrest (CA).MethodsA prospective analysis of patients who were hospitalized at a medical ICU after CPR between December 2018 and March 2020 was conducted. Exclusion criteria were age < 18 years, hospital length of stay < 24 h and traumatic CA. The primary study endpoint was mortality after 6 months and the secondary endpoint neurological outcome assessed by cerebral performance category (CPC). Differences between groups were calculated by using U‑tests and χ2-tests, for survival analysis both univariate and multivariable Cox regression were fitted.ResultsA total of 106 patients were included and the majority were male (71.7%). No statistically significant difference regarding 6‑month mortality between sexes could be shown (hazard risk, HR 0.68, 95% confidence interval, CI 0.35-1.34; p = 0.27). Neurological outcome was also similar between both groups (CPC 1 88% in both sexes after 6 months; p = 1.000). There were no statistically significant differences regarding general characteristics, pre-existing diseases, as well as the majority of clinical and laboratory parameters or measures performed on the ICU.ConclusionIn a single center CPR database no statistically significant sex-specific differences regarding post-resuscitation care, survival and neurological outcome after 6 months were observed.

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