• Sabeen Abid Khan, Mohsina Noor Ibrahim, and Anwar-ul-HaqDepartment of Paediatrics, The Aga Khan University Hospital, Karachi..
• Department of Paediatrics, The Aga Khan University Hospital, Karachi.
• J Coll Physicians Surg Pak. 2015 Dec 1; 25 (12): 878-81.

ObjectiveTo determine the frequency of hyperglycemia in critically ill children admitted in PICU of a tertiary care hospital of Karachi and to compare the mortality of critically ill children with and without hyperglycemia.Study DesignCross-sectional study.Place And Duration Of StudyPaediatrics Intensive Care Unit (PICU) of National Institute of Child Health (NICH), Karachi, from November 2011 to April 2012.MethodologyOne hundred fifty critically ill children admitted to PICU were included. Patients who had fasting blood sugar levels more than 126 mg/dl within 48 hours of admission were included in the hyperglycemic group. The normoglycemic and hyperglycemic groups were followed till 10 days to determine the mortality associated with hyperglycemia.ResultsOut of 150 patients, 82 (54.7%) had hyperglycemia. Mortality rate was 48.7% (n=73/150). However, mortality rate was significantly high 57.3% (n=47) in hyperglycemic patients than non-hyperglycemic patients (p=0.019).ConclusionThe presence of stress-induced hyperglycemia in critically ill patients is a well established marker of poor outcome, and a very high mortality rate. Normoglycemia was associated with favorable outcomes in terms of hospital stay and mortality.

26 keywords...

hide…