• Ocul. Immunol. Inflamm. · Aug 2020

    Ocular Features and Associated Systemic Findings in SARS-CoV-2 Infection.

    • Michele Cavalleri, Maria Brambati, Vincenzo Starace, Luigi Capone, Francesco Nadin, Matteo Pederzolli, Francesca Gorgoni, Carlo Di Biase, Eleonora Corbelli, Marco Battista, Alessio Grazioli Moretti, Domenico Grosso, and Francesco Bandello.
    • Department of Ophthalmology, Scientific Institute San Raffaele, Vita-Salute University , Milan, Italy.
    • Ocul. Immunol. Inflamm. 2020 Aug 17; 28 (6): 916-921.

    PurposesTo describe the prevalence of ocular features among COVID-19 patients and their relationship with clinical data, inflammatory markers and respiratory support therapy (including CPAP); to investigate SARS-CoV-2 in ocular secretions of symptomatic patients.Methods172 COVID-19 patients were evaluated for presence of ocular manifestations. Clinical and laboratory data were also reviewed. Conjunctival swabs were analyzed for SARS-CoV-2 by RT-PCR.ResultsForty-five patients (26.2%) reported ocular manifestations. Patients treated with CPAP were more likely to have ocular abnormalities (p <.01). The presence of ocular symptoms was not associated with more significant alterations on blood tests. Conjunctival swabs from patients with suspect conjunctivitis yielded negative results for SARS-CoV-2.ConclusionsOcular features are not infrequent in COVID-19 patients, but the presence of SARS-CoV-2 in ocular secretions is low. Ocular manifestations in hospitalized COVID-19 patients can also be a consequence of respiratory support therapy. Prevention of possible transmission through ocular secretions is still recommended.

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