• Lidwien Moonen, Erwin Gorter, and Inger Schipper.
• Leiden University Medical Center, Department of Trauma Surgery, Leiden, the Netherlands. Electronic address: moonenlidwien@gmail.com.
• Nutrition. 2021 Jul 1; 87-88: 111192.

AbstractThe prevalence of hypovitaminosis D is currently increasing. A wide variety of diseases and complications are associated with low vitamin D serum concentrations, including poor fracture healing and fracture non-union. A healthy 44-y-old man presented himself with pain due to a non-union of a femoral shaft fracture at 4 y after the initial injury. The fracture had been operated upon three times and was adequately fixated in anatomic position. Hypovitaminosis D was diagnosed, and subsequent supplementation resulted in complete union of the fracture with full pain relief. This case illustrates the importance of adequate serum vitamin D levels in fracture healing, in addition to other fracture healing facilitating factors. With the increasing prevalence of hypovitaminosis D and possibly associated fracture-related complications, routine vitamin D determination should become part of clinical workup in cases of fracture non-union.Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

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