• Postgrad Med J · Sep 2022

    Review

    Colchicine in coronary artery disease.

    • Arnav Katira and Ravish Katira.
    • Department of Medicine, Salford Royal NHS Foundation Trust, Salford, UK arnavkatira@gmail.com.
    • Postgrad Med J. 2022 Sep 1; 98 (1163): 718-721.

    AbstractCoronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Inflammation has been seen to be a key feature of atherosclerosis and CAD, with a raised C-reactive protein being a marker of poor prognosis. Thus, the role of anti-inflammatory agents has been investigated in CAD. Colchicine is a well-known, inexpensive drug with marked anti-inflammatory effects. Here, we discuss the role of colchicine in stable CAD and post-acute coronary syndrome. We suggest that colchicine may play a key role in prevention of cardiovascular events in patients with stable and unstable CAD as colchicine is associated with a reduction in the rate of myocardial infarction and other major cardiovascular outcomes.© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

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