• J Transl Med · Jun 2020

    Letter

    SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines.

    • Giovanni Salvatori, Laura Luberto, Mariano Maffei, Luigi Aurisicchio, Giuseppe Roscilli, Fabio Palombo, and Emanuele Marra.
    • Takis s.r.l, Via di Castel Romano 100, 00128, Rome, Italy.
    • J Transl Med. 2020 Jun 3; 18 (1): 222.

    AbstractCOVID-19 has rapidly spread all over the world, progressing into a pandemic. This situation has urgently impelled many companies and public research institutes to concentrate their efforts on research for effective therapeutics. Here, we outline the strategies and targets currently adopted in developing a vaccine against SARS-CoV-2. Based on previous evidence and experience with SARS and MERS, the primary focus has been the Spike protein, considered as the ideal target for COVID-19 immunotherapies.

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