• S Gergaud, E Lermite, F Butel, C Soltner, and S Lasocki.
• Pôle d'anesthésie-réanimation, université d'Angers, CHU d'Angers, 4, rue Larrey, 49000 Angers, France.
• Ann Fr Anesth Reanim. 2012 May 1;31(5):472-4.

AbstractWe reported the case of a 61-year-old woman, who has been hospitalized in ICU because of an extensive mesenteric ischaemia, involving the small bowel, secondary to a naratriptan overuse. This mesenteric ischaemia was complicated by multiple organ failure and was responsible for extensive small bowel resection and left colectomy. A concomitant abundant absorption of grapefruit juice, a well-known P450 inhibitor, may have enhanced this naratriptan toxicity. This case underscore that an abdominal pain occurring in the context of headache treatment may be related to a mesenteric ischaemia.Copyright © 2012 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

27 keywords...

hide…