• Viktor Szabó, Gábor Halász, and Tibor Gondos.
• Budapest University of Technology and Economics, Department of Hydrodynamic, Systems, 1111 Budapest Műegyetem rkp. 3, Hungary. Electronic address: vszabo@hds.bme.hu.
• Comput. Biol. Med. 2015 Apr 1; 59: 30-34.

AbstractIn the present paper, an attempt was made to find waveform-derived variables that would be useful for a more precise diagnosis of hypovolemia. In attempting this, arterial blood pressure graphs of 18 hypovolemic postoperative patients were analysed using a discrete Fourier transform. Using a paired samples t-test, the amplitude of the first harmonic (A1) is shown to be significantly higher in normovolemic cases than in hypovolemic ones (p < 0.001). Based on the values of A1, a preliminary study was performed in which an additional group of 14 hypovolemic and 14 normovolemic patients were categorized into hypovolemic and normovolemic groups using logistic regression. The method proved to be successful in identifying hypovolemic patients: the prediction was correct in 80% and wrong only in 20%, indicating that A1 is potentially a useful parameter in detecting hypovolemia.Copyright © 2015 Elsevier Ltd. All rights reserved.

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