• Rola N Hamam, Anita W Barikian, Rafic S Antonios, Marwan R Abdulaal, Ramzi M Alameddine, Georges El Mollayess, and Ahmad M Mansour.
• a Department of Ophthalmology , American University of Beirut Medical Center , Beirut , Lebanon and.
• Ocul. Immunol. Inflamm. 2016 Jun 1; 24 (3): 319-26.

PurposeTo evaluate the short-term efficacy of intravitreal adalimumab (IVA) for the treatment of eyes with active noninfectious uveitis.MethodsConsecutive eyes with active noninfectious uveitis were injected with IVA at 0, 2, then every 4 weeks for total of 26 weeks.ResultsSix out of 7 patients (12 of 13 eyes) completed 26 weeks of treatment. One patient (1 eye) failed treatment. Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. And 9 of 10 eyes with vitreous haze had zero haze at 26 weeks. Five out of 8 eyes with macular edema had complete resolution. Median fluorescein angiography score improved from 14 to 4 on last follow-up.ConclusionsIVA was effective in controlling the inflammation, decreasing the macular edema, and improving the best corrected visual acuity in the majority of eyes in this series.

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