• J Gynecol Obst Bio R · Oct 2001

    [Rectal administration of misoprostol for delivery induced hemorrhage. Preliminary study].

    • R Shojai, L Piéchon, C d'Ercole, L Boubli, and J E Pontiès.
    • Service de Gynécologie Obstétrique (Pr L. Boubli), CHU Nord, 15, chemin des Bourrelys, 13015 Marseille. rahashojai@yahoo.com
    • J Gynecol Obst Bio R. 2001 Oct 1; 30 (6): 572-5.

    ObjectiveAssess the efficacy of one misoprostol tablet (Cytotec) in severe delivery-induced hemorrhage on uterine atony after failure of syntocinon.Patients And MethodsA descriptive study was conducted at the Djibouti Army Hospital from September to December 2000. Five patients with severe delivery-induced hemorrhage due to uterine atony unresponsive to syntocinon were give a tablet of misoprostol by rectal administration.ResultsThe hemorrhage ceased in less than 5 minutes in all patients. No immediate side effect was observed.DiscussionThese preliminary findings are encouraging and suggest that further investigations would be useful to assess the beneficial effect of misoprostol by rectal administration for patients with severe delivery-induced hemorrhage due to uterine atony. Case-control studies with a sufficient number of cases should be undertaken to determine the real efficacy of misoprostol in this indication.

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