• Hacı Semih Gürcan, Ayşe Ülgey, Özlem Öz Gergin, Seçkin PehlivanSibelS0000-0003-3215-5616Department of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, Turkey, and Karamehmet Yıldız.
• Department of Anesthesiology and Reanimation, Gümüşhacıköy Government Hospital, Amasya, Turkey
• Turk J Med Sci. 2021 Aug 30; 51 (4): 2120-2126.

Background/AimIn this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on post- procedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI).Materials And MethodsThis study included 100 pediatric patients (2–10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n = 50) or propofol-fentanyl (Group F; n = 50). For sedation induction, intravenous (IV) bolus of 1.2 mg/kg propofol and 1 mg/kg ketamine were administered in Group K, IV bolus of 1.2 mg/kg propofol, and 1 μg/kg fentanyl in Group F. All patients received 0.5 mg/kg IV bolus propofol in additional doses when the Ramsay Sedation Score (RSS) was below 4 for maintenance. Perioperative heart rate, systolic arterial pressure, peripheral oxygen saturation, respiratory rate, and nausea-vomiting scores were recorded for each patient.ResultsThere was no difference between the groups in terms of nausea incidences at the 1st hour. However, the rate of vomiting was significantly higher in Group K.ConclusionIn our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.This work is licensed under a Creative Commons Attribution 4.0 International License.

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