• J Cosmet Dermatol · Mar 2016

    Review

    What do we know about sulforaphane protection against photoaging?

    • Sohely Sikdar, Maria Papadopoulou, and Jacques Dubois.
    • Laboratoire de Chimie Bioanalytique, Toxicologie et Chimie Physique Appliquée, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Brussels, Belgium.
    • J Cosmet Dermatol. 2016 Mar 1; 15 (1): 72-7.

    AbstractSulforaphane (SFN), a natural compound occurring in cruciferous vegetables, has been known for years as a chemopreventive agent against many types of cancer. Recently, it has been investigated as an antioxidant and anti-aging agent, and interesting conclusions have been made over the last decade. SFN demonstrated protective effects against ultraviolet (UV)-induced skin damage through several mechanisms of action, for example, decrease of reactive oxygen species production, inhibition of matrix metalloproteinase expression, and induction of phase 2 enzymes. SFN used as a protective agent against UV damage is a whole new matter, and it seems to be a very promising ingredient in upcoming anti-aging drugs and cosmetics. © 2016 Wiley Periodicals, Inc.

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