• Cleve Clin J Med · May 2021

    Review

    Quetiapine for primary insomnia: Consider the risks.

    • Vania Modesto-Lowe, Agata K Harabasz, and Sophia A Walker.
    • University of Connecticut School of Medicine, Farmington, CT; Quinnipiac University, Hamden, CT; Connecticut Valley Hospital, Middletown, CT vania.modesto-lowe@ct.gov.
    • Cleve Clin J Med. 2021 May 3; 88 (5): 286-294.

    AbstractThe second-generation antipsychotic drug quetiapine (Seroquel) is increasingly being used off-label for treating insomnia in the general population, possibly to avoid standard medications with known addictive qualities and adverse side effects. However, evidence to support using it in this way is scant, and quetiapine is associated with weight gain and other metabolic effects. It must be used cautiously and with appropriate monitoring for adverse effects and abuse.Copyright © 2021 The Cleveland Clinic Foundation. All Rights Reserved.

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