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Future microbiology · Sep 2020
ReviewPathogenesis, clinical manifestations and complications of coronavirus disease 2019 (COVID-19).
- Elaheh Kordzadeh-Kermani, Hossein Khalili, and Iman Karimzadeh.
- Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 141761441, Iran.
- Future Microbiol. 2020 Sep 1; 15: 1287-1305.
AbstractAim: Despite the similarities in the pathogenesis of the beta coronaviruses, the precise infective mechanisms of SARS-CoV-2 remain unclear. Objective: In this review, we aim to focus on the proposed theories behind the pathogenesis of SARS-CoV-2 and highlight the clinical complications related to COVID-19. Methods: We conducted a literature search in Pubmed, Scopus and Google Scholar for the relevant articles regarding clinical complications and pathogenesis of COVID-19. Results: Related articles were included and discussed. Conclusion: Respiratory system and the lungs are the most commonly involved sites of COVID-19 infection. Cardiovascular, liver, kidneys, gastrointestinal and central nervous systems are involved with different frequencies and degrees of severity.
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