• J Cosmet Dermatol · Sep 2011

    Letter Case Reports

    Nodular skin reactions in eyebrow permanent makeup: two case reports and an infection by Mycobacterium haemophilum.

    • Uwe Wollina.
    • J Cosmet Dermatol. 2011 Sep 1; 10 (3): 235-9.

    BackgroundPermanent makeup is becoming more and more popular. The procedures, however, bear some medical risks.AimsWe will describe possible adverse effects of the procedure.MethodsThis is a report of clinical observations.ResultsWe report about two women aged 26 and 47 years, who developed nodules with some delay after permanent tattooing the eyebrows. Clinical, histologic, and laboratory investigations revealed a noninfectious granulomatous reaction not responding to topical calcineurin inhibitor but corticosteroids in the younger patient. In the other woman, an infection by Mycobacterium haemophilum could be identified. A triple combination of clarithromycin, ciprofloxacin, and rifampicin succeeded in clearance of the lesions.ConclusionsAdverse reactions after permanent makeup need a medical evaluation to identify health risks and initiate early treatment.© 2011 Wiley Periodicals, Inc.

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