• Curēus · Aug 2020

    Case Reports

    COVID-19 Associated Coagulopathy in the Setting of Underlying Malignancy.

    • Su Lin Lim, Kok Hoe Chan, Jihad Slim, Gunwant Guron, and Hamid S Shaaban.
    • Internal Medicine, Saint Michael's Medical Center, Newark, USA.
    • Cureus. 2020 Aug 28; 12 (8): e10095.

    AbstractCoronavirus disease 2019 (COVID-19) associated coagulopathy is a well-recognized predictor for morbidity and mortality in COVID-19 patients. Both deep vein thrombosis (DVT) and pulmonary embolism (PE) have been reported in COVID-19 patients. Nonetheless, there are no consensus guidelines on the use of therapeutic coagulation in this group of patients. We herein present a unique case of a confirmed COVID-19 patient with metastatic ovarian cancer who presented with DVT and PE despite being on therapeutic anticoagulation, highlighting the unpredictability of COVID-19 associated coagulopathy. This case study raises the awareness that the thrombophilic state in metastatic malignancies is potentially augmented by COVID-19. We also discuss the complexity of making anticoagulation treatment decision in COVID-19 patients in the absence of evidence-based guidelines.Copyright © 2020, Lim et al.

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