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J. Am. Acad. Dermatol. · Nov 1997
Case ReportsTarget lesions on the lips: childhood herpes simplex associated with erythema multiforme mimics Stevens-Johnson syndrome.
- W L Weston, J G Morelli, and M Rogers.
- Royal Alexandria Hospital for Children, Sydney, Australia.
- J. Am. Acad. Dermatol. 1997 Nov 1; 37 (5 Pt 2): 848-50.
AbstractErythema multiforme and Stevens-Johnson syndrome are both characterized by areas of epithelial necrosis. An important clinical feature that distinguishes the two is the extensive mucosal necrosis in Stevens-Johnson syndrome but not in erythema multiforme. Because significant and serious complications may develop with Stevens-Johnson syndrome and not with erythema multiforme, it is important to differentiate between the conditions. We describe three boys with herpes simplex virus-associated erythema multiforme who had severe necrosis of the lips develop and were initially diagnosed with Stevens-Johnson syndrome. The lip lesions were large target lesions of erythema multiforme rather than the extensive necrosis seen in Stevens-Johnson syndrome and all three had a benign course.
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