• Saudi J Kidney Dis Transpl · May 2017

    Case Reports

    Recurrent syndrome of inappropriate antidiuretic hormone secretion due to tolterodine in an elderly male patient.

    • Abdullah K Alhwiesh, Husain Alsharani, Eman Fathi Ibrahim, Zaid Alanazi, Bushra Ahmed AlGhamdi, Nadia Alaudah, Feras Alzahrani, Adnan Alsarawi, Ashwaqu Almohaws, and Ibraheem Saeed Abdurrahman.
    • Department of Internal Medicine, Division of Nephrology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Al-Khobar, Saudi Arabia.
    • Saudi J Kidney Dis Transpl. 2017 May 1; 28 (3): 625-628.

    AbstractHyponatremia is defined as serum sodium of <135 mmol/L and equates with a low serum osmolality once translocational hyponatremia and pseudohyponatremia are ruled out. True hyponatremia develops when normal urine-diluting mechanisms are disturbed. In elderly patients, this complication is not uncommon, especially in nursing homes and assisted living facilities. Medications are often the most common cause of hyponatremia in these patients. Herewith, we reported a 65-year-old Saudi male, a known case of benign prostatic hypertrophy and hypertension, who developed recurrent hyponatremia secondary to tolterodine. To our knowledge, this is the fifth case reported in literature of such association.

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