• Curēus · Aug 2018

    Case Reports

    Naphthalene Toxicity: Methemoglobinemia and Acute Intravascular Hemolysis.

    • Giselle Volney, Michael Tatusov, Andy C Yen, and Nune Karamyan.
    • Internal Medicine, Ross University School of Medicine, Roseau, DMA.
    • Cureus. 2018 Aug 15; 10 (8): e3147.

    AbstractNaphthalene poisoning is a rare form of toxicity that may occur after ingestion, inhalation, or dermal exposure to naphthalene-containing compounds such as mothballs. Clinically, patients present with acute onset of dark brown urine, watery diarrhea, and non-bloody bilious vomiting 48-96 hours after exposure. Vital sign abnormalities include fever, tachycardia, hypotension, and persistent pulse oximetry readings of 84%-85% despite oxygen supplementation. Laboratory workup demonstrates hyperbilirubinemia with indirect predominance, hemolytic anemia, methemoglobinemia, and renal dysfunction. Treatment options include supportive care, red cell transfusion, ascorbic acid, methylene blue, and N-acetylcysteine. We present a case of naphthalene toxicity in a 20-year-old autistic male, who improved with supportive care, red blood cell transfusion, and ascorbic acid.

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