• Wuyuntana Wang, Gegentana School of Mongol medicine, Inner Mongolia University for Nationalities, Tongliao, China., Tonglaga Department of Mongolian Dermatology, Affiliated Hospital of Inner Mongolia University for Nationalities, Tongliao, China. Department of, Bagenna https://orcid.org/0000-0002-9815-7975 School of Mongol medicine, Inner Mongolia University for Nationalities, Tongliao, China., and Yuanhong Li.
• School of Mongol medicine, Inner Mongolia University for Nationalities, Tongliao, China.
• J Cosmet Dermatol. 2019 Aug 1; 18 (4): 1009-1013.

BackgroundAlopecia areata (AA) is a relatively common dermatosis with the sudden burst of hair loss on the scalp and other hair-bearing regions. However, because of high relapse and side effects, no satisfactory therapy has been widely accepted.ObjectiveTo observe the efficiency and safety of the combination therapy of a nonablative fractional (NAF) laser and topical minoxidil for AA.MethodsEight Chinese AA patients were included in this study. These patients received 10 treatments every two weeks. At every time, the subject was given 10 to 15 mJ of energy with a total intensity of 300 spots/cm2 . After the laser treatment, a topical 5% minoxidil tincture was immediately applied twice daily and continued until the final laser treatment.ResultsHair regrowth was observed 1-2 months after treatment. There was complete regrowth in 2 patients, and the lesions of 2 children with alopecia universalis were covered with 30% and 50% regrowth, respectively. All patients except 1 had no relapse at the 1-year follow-up examination.ConclusionThe combination of nonablative laser and topical minoxidil may be a good alternative therapy for AA patients, including alopecia totalis and alopecia universalis, without systemic and local side effects.© 2019 Wiley Periodicals, Inc.

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