• G Gueret, M Guillouet, V Vermeersch, E Guillard, H Talarmin, B-V Nguyen, F Rannou, M-A Giroux-Metges, J-P Pennec, and Y Ozier.
• Pôle anesthésie réanimations soins intensifs blocs opératoires urgences (ARSIBOU), CHRU de Brest, boulevard Tanguy-Prigent, 29200 Brest, France; Laboratoire de physiologie, faculté de médecine et des sciences de la santé, EA 1274 (mouvement, sport santé), université de Bretagne-Occidentale, 22, avenue Camille-Desmoulins, 29200 Brest, France; Université européenne de Bretagne, 5, boulevard Laennec, 35000 Rennes, France. Electronic address: gildas.gueret@chu-brest.fr.
• Ann Fr Anesth Reanim. 2013 Sep 1;32(9):580-91.

AbstractICU acquired neuromyopathy (IANM) is the most frequent neurological pathology observed in ICU. Nerve and muscle defects are merged with neuromuscular junction abnormalities. Its physiopathology is complex. The aim is probably the redistribution of nutriments and metabolism towards defense against sepsis. The main risk factors are sepsis, its severity and its duration of evolution. IANM is usually diagnosed in view of difficulties in weaning from mechanical ventilation, but electrophysiology may allow an earlier diagnosis. There is no curative therapy, but early treatment of sepsis, glycemic control as well as early physiotherapy may decrease its incidence. The outcomes of IANM are an increase in morbi-mortality and possibly long-lasting neuromuscular abnormalities as far as tetraplegia.Copyright © 2013 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

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