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Semin Cutan Med Surg · Mar 2011
New agents for prevention of ultraviolet-induced nonmelanoma skin cancer.
- William L Camp, Jennifer W Turnham, Mohammad Athar, and Craig A Elmets.
- Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
- Semin Cutan Med Surg. 2011 Mar 1; 30 (1): 6-13.
AbstractWith the incidence of nonmelanoma skin cancer on the rise, current prevention methods, such as the use of sunscreens, have yet to prove adequate to reverse this trend. There has been considerable interest in identifying compounds that will inhibit or reverse the biochemical changes required for skin cancers to develop, either by pharmacologic intervention or by dietary manipulation. By targeting different pathways identified as important in the pathogenesis of nonmelanoma skin cancers, a combination approach with multiple agents or the addition of chemopreventative agents to topical sunscreens may offer the potential for novel and synergistic therapies in treating nonmelanoma skin cancer.2011 Elsevier Inc. All rights reserved.
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