• Meftun Culpan, Ferhat Keser, Hazal Cansu Acar, Alper Otunctemur, Eyup Veli Kucuk, Selcuk Erdem, Murat Ozer, Ugur Tolga Sen, Enes Degirmenci, Rifat Ergul, Ramazan Gokhan Atis, and Asif Yildirim.
• Department of Urology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
• Int. J. Clin. Pract. 2021 Sep 1; 75 (9): e14490e14490.

PurposeTo evaluate the impact of delay in cystoscopic surveillance on recurrence and progression rates in non-muscle-invasive bladder cancer (NMIBC).Materials And MethodsA total of 407 patients from four high-volume centres with NMIBC that applied for follow-up cystoscopy were included in our study prospectively. Patients' demographics and previous tumour characteristics, the presence of tumour in follow-up cystoscopy, the pathology results of the latest transurethral resection of bladder tumour (if tumour was detected) and the delay in cystoscopy time were recorded. Our primary outcomes were tumour recurrences detected by follow-up cystoscopy and progression. Multivariate logistic regression analysis was performed using the possible factors identified with univariate analyses (P values ≤ .2).ResultsA total of 105 patients (25.8%) had tumour recurrence in follow-up cystoscopy, and 20 (5.1%) of these patients had disease progression according to grade or stage. In multivariate analysis, the number of recurrences (OR: 1.307, P < .001) and the cystoscopy delay time (62-147 days, OR: 2.424, P = .002; >147 days, OR: 4.883, P < .001) were significant risk factors for tumour recurrence on follow-up cystoscopy; the number of recurrences (OR: 1.255, P = .024) and cystoscopy delay time (>90 days, OR: 6.704, P = .002) were significant risk factors for tumour progression.ConclusionsThis study showed that a 2-5 months of delay in follow-up cystoscopy increases the risk of recurrence by 2.4-fold, and delay in cystoscopy for more than 3 months increases the probability of progression by 6.7-fold. We suggest that cystoscopic surveillance should be done during the COVID-19 pandemic according to the schedule set by relevant guidelines.© 2021 John Wiley & Sons Ltd.

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