• Jeanette Janaina Jaber Lucato, Mauro Roberto Tucci, Guilherme Paula Pinto Schettino, Alexander B Adams, Carolina Fu, Germano Forti, Carlos Roberto Ribeiro de Carvalho, and Rogério de Souza.
• Rua Professor Pedreira de Freitas, 372 - Apt 101E, CEP 03312-052, Sao Paulo, Brazil. jeanettejaber@yahoo.com
• Resp Care. 2005 May 1; 50 (5): 636-43.

IntroductionWhen endotracheal intubation is required during ventilatory support, the physiologic mechanisms of heating and humidifying the inspired air related to the upper airways are bypassed. The task of conditioning the air can be partially accomplished by heat-and-moisture exchangers (HMEs).ObjectivesTo evaluate and compare with respect to imposed resistance, different types/models of HME: (1) dry versus saturated, (2) changing inspiratory flow rates.Materials And MethodsEight different HMEs were studied using a lung model system. The study was conducted initially by simulating spontaneous breathing, followed by connecting the system directly to a mechanical ventilator to provide pressure-support ventilation.ResultsNone of the encountered values of resistance (0.5\N3.6 cm H(2)O/L/s) exceeded the limits stipulated by the previously described international standard for HMEs (International Standards Organization Draft International Standard 9360-2) (not to exceed 5.0 cm H(2)O with a flow of 1.0 L/s, even when saturated). The hygroscopic HME had less resistance than other types, independent of the precondition status (dry or saturated) or the respiratory mode. The hygroscopic HME also had a lesser increase in resistance when saturated. The resistance of the HME was little affected by increases in flow, but saturation did increase resistance in the hydrophobic and hygroscopic/hydrophobic HME to levels that could be important at some clinical conditions.ConclusionsResistance was little affected by saturation in hygroscopic models, when compared to the hydrophobic or hygroscopic/hydrophobic HME. Changes in inspiratory flow did not cause relevant alterations in resistance.

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