• Pak J Med Sci · May 2021

    Association amid the comorbidity of Diabetes Mellitus in patients of Active Tuberculosis in Pakistan: A matched case control study.

    • Nadia Khalid, Farah Ahmad, and Farhan Muhammad Qureshi.
    • Dr. Nadia Khalid, MBBS. Senior Lecturer, Department of Community Health Sciences, Bahria University Medical & Dental College, Karachi, Pakistan.
    • Pak J Med Sci. 2021 May 1; 37 (3): 816-820.

    ObjectivesThis study aims to test the association between diabetes and tuberculosis.MethodsIt is a matched case control study conducted in tertiary care hospitals in 2019-2020. Cases and controls were 144 each, selected on the basis of an odds ratio of 2 at 95% confidence interval with a significance level of 5%. Cases of pulmonary tuberculosis were selected through consecutive sampling technique, either visiting OPD or admitted in hospital. Controls were taken from the general population and frequency matching was done based on age, gender and socioeconomic status. Data was collected through structured questionnaire after taking written consent. Data was analyzed on SPSS version 23. Binary Logistic regression model was applied for finding association between the risk factors and the disease. P value <0.05 was considered statistically significant.ResultsOut of all cases and controls, 45% and 20% were diabetics respectively. The association between the risk factors and tuberculosis was estimated by univariate analysis, positive association was found between diabetes and tuberculosis (OR= 3.32), a high frequency of diabetes in cases as compared to controls were observed with a highly significant p- value (<.001).ConclusionsThis study provides evidence for a strong positive association between tuberculosis and diabetes.Copyright: © Pakistan Journal of Medical Sciences.

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