• Pak J Med Sci · May 2021

    The association of symptoms of overactive bladder with pelvic organ prolapse and its improvement after pelvic reconstructive surgery.

    • Saida Abrar, Raheela Mohsin Rizvi, and Nida Zahid.
    • Dr. Saida Abrar, Department of Gynecology/Obstetrics, Clinical Fellow Urogynecology and Pelvic Reconstructive Surgery, Aga Khan University Hospital, Karachi, Pakistan.
    • Pak J Med Sci. 2021 May 1; 37 (3): 897-902.

    ObjectivesThis study asseses the association of overactive bladder symptoms and pelvic organ prolapse severity and evaluates the effect of pelvic reconstructive surgery on overactive bladder (OAB) symptoms in women with pelvic organ prolapse (POP). It also looks into any pre and post-operative factors responsible for persistent postoperative OAB symptoms.MethodsThis was a retrospective cross-sectional study conducted at the Aga Khan University Hospital, Karachi between 1st January 2014 and 31st December 2018. In this study women presenting with POP and concommitent OAB who underwent surgery for site specific defects, measured using Pelvic Organ Prolapse Quantification (POP-Q) staging system. OAB was defined as presence of urinary frequency, urinary urgency incontinence (UUI) and an affirmative response to item #15 and/or item #16 of the Pelvic Floor Distress Inventory (PFDI), which was used both pre and postoperatively. Primary outcome of the study was to find complete resolution or improvement of urinary frequency and UUI on the PFDI, 24 months after surgery. The secondary outcome was to see persistent OAB postoperatively and the factors associated with it.ResultsOveractive bladder (OAB) symptoms improved significantly regardless of the severity of prolapse at 24 months postoperative period. Body mass index (BMI) and postoperative constipation were the only statistically significant variables associated with persistent OAB symptoms postoperatively.ConclusionsSurgical correction of POP results in significant improvement in symptoms of OAB, in all stages of POP and co-existing OAB. However women with high BMI and post-operative constipation may be prone to persistent frequency and/or UUI.Copyright: © Pakistan Journal of Medical Sciences.

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