• Hong-Xia Zhang, Li-Li Jia, Xu-Hong Hou, Jun-Xi Lu, Hui-Juan Lu, Jie Du, Hui-Lin Gu, and Wei-Ping Jia.
• Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of Endocrinology & Metabolism of Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
• Zhonghua Yi Xue Za Zhi. 2009 Jul 7; 89 (25): 1749-52.

ObjectiveTo determine the prevalence and risk factors of diabetic retinopathy (DR) in the Diabetes Mellitus (DM) and impaired glucose regulation (IGR) population in Shanghai Community.MethodsDR screening after the epidemiologic study of metabolic syndrome in Huayang and Caoyang Community, Shanghai was conducted among 1300 patients with DM or IGR during June 2005 and March 2006, Digital non-mydriatic fundus photography was performed for each eye in all subjects. Other factors, including diabetes related history, BMI, WHR, fasting plasma glucose, HbA1c, serum lipid and blood pressure were also assessed. 642 patients, 312 males and 330 females, aged 65 +/- 13, with complete data were enrolled into the analysis.ResultsThe prevalence of DR was 19.9% in the diabetic population, and the prevalence of mild, moderate, severe non-proliferative retinopathy and proliferative retinopathy was 12.0%, 5.1%, 2.3% and 0.5%, respectively; the prevalence of DR in IGR reached 8.0%. Logistic regression analysis revealed that HbA1c level and diabetes duration were both independently associated with diabetic retinopathy.ConclusionThe prevalence of DR was high in both DM and IGR population. Bad blood glucose control and long diabetes duration both increased occurrence of DR.

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