• Pablo Álvarez-Maldonado, Grisel Hernández-Ríos, Julio C Ambríz-Mondragón, Julián A Gordillo-Mena, Diana F Morales-Serrano, Arturo Reding-Bernal, and Alejandro Hernández-Solis.
• Department of Pulmonology and Thoracic Surgery.
• Gac Med Mex. 2021 Jan 1; 157 (1): 97-101.

IntroductionCOVID-19-associated mortality in patients who require mechanical ventilation is unknown in the Mexican population.ObjectiveTo describe the characteristics of Mexican patients with COVID-19 who required mechanical ventilation.MethodsObservational cohort study carried out in an intensive care unit from March 25 to July 17, 2020. Data were obtained from a prospective database and electronic medical records, and were analyzed with the chi-square test, Fisher's exact test or Mann-Whitney's U-test.ResultsOne hundred patients required mechanical ventilation; median age was 56 years, 31 % were females and 97 % were Latin American. Most common comorbidities were obesity (36 %), diabetes (26 %), hypertension (20 %), and chronic or end-stage kidney disease (10 %). At the end of the analysis, 11 patients remained in the ICU, 31 had been discharged alive and 58 (65.2 %) died; survivors were younger, had lower scores on severity and organ dysfunction scales, lower levels of C-reactive protein at ICU admission, were less likely to receive hemodialysis and vasopressors, and had longer hospital and ICU stays.ConclusionsThis study adds information on the presentation and results of SARS-CoV-2-infected patients who require mechanical ventilation.Copyright: © 2020 Permanyer.

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