• J. Toxicol. Clin. Toxicol. · Jan 1999

    Case Reports

    Oral frostbite injury from intentional abuse of a fluorinated hydrocarbon.

    • D A Kuspis and E P Krenzelok.
    • Pittsburgh Poison Center, Children's Hospital of Pittsburgh, PA 15213, USA.
    • J. Toxicol. Clin. Toxicol. 1999 Jan 1; 37 (7): 873-5.

    BackgroundA serious but rarely reported complication of halogenated hydrocarbon inhalation abuse is severe mucosal frostbite.Case ReportA 16-year-old male attempted to "get high" by inhaling airbrush propellant which contained 1,1-difluoroethane (CAS #75-376). The patient lost consciousness and upon awakening his lips and tongue were frozen. He suffered first- and second-degree burns of the larynx with vocal cord involvement and first-degree burns of the trachea, main stem bronchi, and esophagus. The oral cavity had second- and third-degree burns which required debridement.ConclusionThis case demonstrates the unusual but severe damage that can occur with the abuse of fluorinated hydrocarbons.

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